Simulation design of a binding-pocket structure of natural enzymes in MOFs for enhanced catalytic activity

Autor:	Weiran Zhu, Chen Chen, Zuorui Wen, Lijun Ding, Jie Wei, Jing Qian, Nan Hao, Kun Wang
Rok vydání:	2022
Předmět:	Materials Chemistry Metals and Alloys Ceramics and Composites Metal Nanoparticles Gold General Chemistry Horseradish Peroxidase Metal-Organic Frameworks Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials
Zdroj:	Chemical Communications. 58:6745-6748
ISSN:	1364-548X 1359-7345
DOI:	10.1039/d2cc01634f
Popis:	We demonstrated that the activity gap between metal-organic frameworks (Fe) and horseradish peroxidase could be bridged by simulating the binding-pocket structure and adding active centers. This customized structure promoted the activation and enrichment of substrates, and addition of gold nanoparticles led to activity superposition and synergistic enhancement.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cca8ad95dd2b5219111d5d3af342e7f https://doi.org/10.1039/d2cc01634f Zobrazit plný text záznamu