Generation of induced pluripotent stem cells from two ADHD patients and two healthy controls

Autor:	Yde Ohki, Cristine Marie, Walter, Natalie Monet, Rickli, Michelle, Van Puyenbroeck, Pakita, Döring, Christian, Hoffmann, Per, Herms, Stefan, Maria Werling, Anna, Walitza, Susanne, Grünblatt, Edna
Přispěvatelé:	University of Zurich
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	10076 Center for Integrative Human Physiology 610 Medicine & health Cell Biology General Medicine 10058 Department of Child and Adolescent Psychiatry 10064 Neuroscience Center Zurich Developmental Biology
Zdroj:	Stem Cell Research, 69
ISSN:	1873-5061 1876-7753
Popis:	Attention-deficit hyperactivity disorder is a neurodevelopmental disorder which prevalence has been increasing in the past decades, affecting more than 5% of children, adolescents worldwide. Regarding etiology, polygenic, environmental factors contribute to the occurrence of ADHD even though molecular mechanisms are not known. Understanding the pathophysiology in patient-specific cells is crucial for the discovery of potential predictive markers, the establishment of new therapeutic targets. In this study, we generated further lines from ADHD patients, healthy controls using Sendai virus transduction, which may help on the study of ADHD at the molecular, cellular levels. Stem Cell Research, 69 ISSN:1873-5061 ISSN:1876-7753
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cc6d67a209c5c6652fec463bc3287e2 https://hdl.handle.net/20.500.11850/607008 Zobrazit plný text záznamu