Effect of neurodevelopmental treatment in children with congenital Zika syndrome: A pilot study

Autor: Wirtud I M Müller, Gabriela L Gama, Marcia C D Borges, Bárbara M A M Bastos, Janiele S Tavares, Emanuela S Barros, Jousilene S Tavares, Melania M R Amorim, Adriana Melo
Rok vydání: 2022
Předmět:
Zdroj: Journal of Paediatrics and Child Health. 58:2008-2015
ISSN: 1440-1754
1034-4810
DOI: 10.1111/jpc.16139
Popis: To evaluate the effects of neurodevelopmental treatment (NDT) in children with congenital Zika syndrome (CZS).This prospective, interventional cohort study involved children with CZS undergoing follow-up at a specialist centre in northeastern Brazil. The duration of the proposed NDT protocol was 1 year, with 45-min sessions delivered one to five times weekly. Motor function, weight, height, head circumference and the incidence of comorbidities were evaluated in children before protocol initiation and then at 3, 6 and 12 months of treatment.Thirty children were evaluated (age mean 30.1 ± 3 months). Motor function improved from baseline to 6 months (P = 0.001). No difference in weight and head circumference z-score (P = 0.51 and P = 0.29, respectively), but an increase in height z-score (P 0.001) was observed over the evaluation period. There was a reduction in the incidence of upper respiratory tract infections, pneumonia and urinary tract infections over the follow-up period.NDT proved to be a viable treatment approach that can improve motor function and reduce the incidence of comorbidities in children with CZS, while having no harmful effects on their growth.
Databáze: OpenAIRE
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