Cellular uptake and biocompatibility of bismuth ferrite harmonic advanced nanoparticles

Autor: Jean-Pierre Wolf, Adriele Prina-Mello, Bashir M. Mohamed, Yannick Mugnier, Ronan Le Dantec, Thomas Jüstel, Yuri Volkov, Sebastian Schwung, Luigi Bonacina, Daniel Rytz, Sandrine Gerber-Lemaire, Ciaran Manus Maguire, Stéphanie Hwu, Davide Staedler, Andrii Rogov, Solène Passemard, Thibaud Magouroux
Přispěvatelé: Group of Applied Physics [Geneva] (GAP), University of Geneva [Switzerland], FEE Gmbh, FEE GmBh, Laboratoire SYstèmes et Matériaux pour la MEcatronique (SYMME), Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry]), Symme, Univ. Savoie Mont Blanc
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Materials science
Biocompatibility
Biomedical Engineering
Contrast Media
Pharmaceutical Science
Medicine (miscellaneous)
Nanoparticle
chemistry.chemical_element
FOS: Physical sciences
Bioengineering
Nanotechnology
ddc:500.2
Ferric Compounds
Matériaux et outils pour la santé
Bismuth
chemistry.chemical_compound
Nanophotonic
Coated Materials
Biocompatible
Cell Line
Tumor
Materials Testing
Cell Behavior (q-bio.CB)
Humans
General Materials Science
Physics - Biological Physics
Cytotoxicity
[SPI.MECA.GEME] Engineering Sciences [physics]/Mechanics [physics.med-ph]/Mechanical engineering [physics.class-ph]
Non-linear imaging
ComputingMilieux_MISCELLANEOUS
Bismuth ferrite
PEGylation
3. Good health
Squamous carcinoma
[SPI.MECA.GEME]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Mechanical engineering [physics.class-ph]
chemistry
Biological Physics (physics.bio-ph)
FOS: Biological sciences
Nanophotonics
Nanoparticles
Molecular Medicine
Quantitative Biology - Cell Behavior
Ethylene glycol
Zdroj: Nanomedicine: Nanotechnology, Biology and Medicine
Nanomedicine: Nanotechnology, Biology and Medicine, Elsevier, 2014, p. 815-824
Nanomedicine, Vol. 11, No 4 (2015) pp. 815-824
ISSN: 1549-9634
Popis: Bismuth Ferrite (BFO) nanoparticles (BFO-NP) display interesting optical (nonlinear response) and magnetic properties which make them amenable for bio-oriented applications as intra- and extra membrane contrast agents. Due to the relatively recent availability of this material in well dispersed nanometric form, its biocompatibility was not known to date. In this study, we present a thorough assessment of the effects of in vitro exposure of human adenocarcinoma (A549), lung squamous carcinoma (NCI-H520), and acute monocytic leukemia (THP-1) cell lines to uncoated and poly(ethylene glycol)-coated BFO-NP in the form of cytotoxicity, haemolytic response and biocompatibility. Our results support the attractiveness of the functional-BFO towards biomedical applications focused on advanced diagnostic imaging.
Word Count: 109 Complete Word Count (body text and figure legends) : 4886 Number of Figures: 6 Number of Tables: 0 Number of reference: 45
Databáze: OpenAIRE
Externí odkaz: