Serum Lipid Profile in Patients with Cholelithiasis

Autor: Rakesh Pokhrel, Binod Aryal, Parshal Bhandari
Rok vydání: 2019
Předmět:
Zdroj: Online Türk Sağlık Bilimleri Dergisi, Vol 4, Iss 2, Pp 139-147 (2019)
ISSN: 2459-1467
Popis: This research aims to correlate status of lipid profile in the patients diagnosed with cholelithiasis. It is an observational case control study, completed in the Biochemistry department of Tribhuvan University and Teaching Hospital (TUTH). Total 100 subjects were selected and divided in two groups. The groups consisted of 50 patients with cholelithiasis (group A) and 50 healthy control groups (group B). The research was completed within a time of eight months commencing from 1st March 2016 to 31st October 2016. Confirmation of cholelithiasis was performed with ultrasound studies by radiologist. Selection of group A and group B were done on basis of radiological findings. Fasting blood samples for lipid profiles of all subjects were collected and lipid profile tests done in bio-chemistry lab. Self-designed form was used for documentation of different parameters of subjects. Triglyceride (TG) and High-Density Lipids (HDL) were found to be statically significant (p=0.005 and p=0. 001, respectively). Mean TG level in patients with cholelithiasis (1.9 mmol/l) was found higher than in normal cases (1.45 mmol/l). Mean HDL level in patients (0.95 mmol/l) was lower than normal cases with (1.05mmol/l). In conclusion, we think that lipid profiles altered in patients with cholelithiasis.
Databáze: OpenAIRE