Acceptability, effectiveness and costeffectiveness of blended cognitivebehavioural therapy (bCBT) versus face-toface CBT (ftfCBT) for anxiety disorders in specialised mental health care: A 15-week randomised controlled trial with 1-year followup
| Autor: | Leona Hakkaart-van Roijen, Jeroen Koning, Geke Romijn, Neeltje M. Batelaan, Heleen Riper, Friederike Benning, Anton J.L.M. van Balkom, Aart de Leeuw |
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| Přispěvatelé: | Psychiatry, APH - Mental Health, APH - Global Health, APH - Societal Participation & Health, Erasmus School of Economics, General Practice, Health Economics (HE), Health Technology Assessment (HTA), Clinical Psychology |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Cost effectiveness Economics Cost-Benefit Analysis Beck Anxiety Inventory Science Cost-Effectiveness Analysis Social Sciences Neuropsychiatric Disorders Neuroses law.invention Quality of life (healthcare) Health Economics Randomized controlled trial SDG 3 - Good Health and Well-being law Health care Mental Health and Psychiatry Medicine and Health Sciences Humans Medicine Psychiatry Multidisciplinary Cognitive Behavioral Therapy business.industry Panic disorder Social anxiety Middle Aged medicine.disease Anxiety Disorders Telemedicine Economic Analysis Health Care Quality of Life Anxiety Panic Disorder Female medicine.symptom business Mental Health Therapies Follow-Up Studies Research Article Social Anxiety Disorder |
| Zdroj: | PLoS ONE, 16(11 November):e0259493. Public Library of Science PLoS ONE, Vol 16, Iss 11 (2021) PLoS ONE, 16(11):e0259493. Public Library of Science PLoS ONE PLoS ONE, Vol 16, Iss 11, p e0259493 (2021) Romijn, G, Batelaan, N, Koning, J, Van Balkom, A, De Leeuw, A, Benning, F, Van Roijen, L H & Riper, H 2021, ' Acceptability, effectiveness and costeffectiveness of blended cognitivebehavioural therapy (bCBT) versus face-toface CBT (ftfCBT) for anxiety disorders in specialised mental health care : A 15-week randomised controlled trial with 1-year followup ', PLoS ONE, vol. 16, no. 11 November, e0259493 . https://doi.org/10.1371/journal.pone.0259493 Romijn, G, Batelaan, N, Koning, J, Van Balkom, A, De Leeuw, A, Benning, F, Van Roijen, L H & Riper, H 2021, ' Acceptability, effectiveness and costeffectiveness of blended cognitivebehavioural therapy (bCBT) versus face-toface CBT (ftfCBT) for anxiety disorders in specialised mental health care : A 15-week randomised controlled trial with 1-year follow-up ', PLOS ONE, vol. 16, no. 11, e0259493 . https://doi.org/10.1371/journal.pone.0259493 Romijn, G, Batelaan, N, Koning, J, van Balkom, A, de Leeuw, A, Benning, F, van Roijen, L H & Riper, H 2021, ' Acceptability, effectiveness and costeffectiveness of blended cognitivebehavioural therapy (bCBT) versus face-toface CBT (ftfCBT) for anxiety disorders in specialised mental health care : A 15-week randomised controlled trial with 1-year followup ', PLoS ONE, vol. 16, no. 11 November, e0259493 . https://doi.org/10.1371/journal.pone.0259493 |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0259493 |
| Popis: | Background Anxiety disorders are highly prevalent and cause substantial economic burden. Blended cognitive-behavioural therapy (bCBT), which integrates Internet-based CBT and face-to-face CBT (ftfCBT), is an attractive and potentially cost-saving treatment alternative to conventional CBT for patients with anxiety disorders in specialised mental health care. However, little is known about the effectiveness of bCBT in routine care. We examined the acceptability, effectiveness and cost-effectiveness of bCBT versus ftfCBT in outpatient specialised care to patients with panic disorder, social anxiety disorder and generalised anxiety disorder. Methods and findings Patients with anxiety disorders were randomised to bCBT (n = 52) or ftfCBT (n = 62). Acceptability of bCBT and ftfCBT were evaluated by assessing treatment preference, adherence, satisfaction and therapeutic alliance. Costs and effects were assessed at post-treatment and one-year follow-up. Primary outcome measure was the Beck Anxiety Inventory (BAI). Secondary outcomes were depressive symptoms, general psychopathology, work and social adjustment, quality of life and mastery. Incremental cost-effectiveness ratios (ICERs) were computed from societal and healthcare perspectives by calculating the incremental costs per incremental quality-adjusted life year (QALY). No significant differences between bCBT and ftfCBT were found on acceptability or effectiveness measures at post-treatment (Cohen’s d between-group effect size on BAI = 0.15, 95% CI −0.30 to 0.60) or at one-year follow-up (d = −0.38, 95% CI −0.84 to 0.09). The modelled point estimates of societal costs (bCBT €10945, ftfCBT €10937) were higher and modelled point estimates of direct medical costs (bCBT €3748, ftfCBT €3841) were lower in bCBT. The acceptability curves showed that bCBT was expected to be a cost-effective intervention. Results should be carefully interpreted due to the small sample size. Conclusions bCBT appears an acceptable, clinically effective and potentially cost-saving alternative option for treating patients with anxiety disorders. Trials with larger samples are needed to further investigate cost-effectiveness. Trial registration Netherlands Trial Register: NTR4912. |
| Databáze: | OpenAIRE |
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