Previously published ethno-pharmacological reports reveal the potentiality of plants and plant-derived products used as traditional home remedies by Bangladeshi COVID-19 patients to combat SARS-CoV-2

Autor: A T M Rafiqul Islam, Jannatul Ferdousi, Shahinozzaman
Rok vydání: 2021
Předmět:
Ethnobotany
HEp-2 cells
Epithelial cells of human larynx carcinoma
H1N1
Hemagglutinin Type 1 and Neuraminidase Type 1
HLAC
Human lymphoid aggregate cultures
MDCK
Madin-Darby Canine Kidney cell lines
MCP-1
Monocyte chemoattractant protein-1
Sore throat
IL
Interleukin
SARS
Severe acute respiratory syndrome
MERS
Middle East respiratory syndrome
Biology (General)
Medicinal plants
Huh-7
Human hepatocyte-derived carcinoma cell line
Bangladesh
Traditional medicine
food and beverages
ICU
Intensive care unit
TNF-β
Tumor necrosis factor‐beta
FRhk-4cells
Fetal rhesus monkey kidney cells
IBD
Inflammatory bowel disease
Original Article
Chills
MARC-145 cells
African green monkey kidney cell line
medicine.symptom
General Agricultural and Biological Sciences
BAL
Bronchoalveolar lavage
VERO cell lines
African green monkey kidney cell lines
Coronavirus disease 2019 (COVID-19)
QH301-705.5
Traditional home remedies
TNF‐α
Tumor necrosis factor‐alpha
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
HeLa
Human epithelial cervical carcinoma cell lines
COPD
Chronic obstructive pulmonary disease
NF-κB
Nuclear factor-kappaB
CHO-K1
Wild-type Chinese hamster ovary CHO-K1 cells
CIK
Ctenopharyngodon idellus kidney Cell line
BALF
Bronchoalveolar lavage fluid
medicine
CRFK
Crandell-Reese feline kidney cells
EPO
Eosinophil peroxidase
Home Remedies
EGCG
Epigallocatechin-3-gallate
ComputingMethodologies_COMPUTERGRAPHICS
Th
T-helper
Asthma
CRD
Complex chronic respiratory disease
business.industry
COVID-19
RT-PCR
Reverse transcription polymerase chain reaction
medicine.disease
HEK293T
Human embryonic kidney cells
IFN‐γ
Interferon‐gamma
IgE
Immunoglobulin E
MEF
Mouse embryonic fibroblast cells
PBMCs
Peripheral Blood Mononuclear Cells
business
Zdroj: Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences, Vol 28, Iss 11, Pp 6653-6673 (2021)
ISSN: 1319-562X
DOI: 10.1016/j.sjbs.2021.07.036
Popis: Graphical abstract
Several plants have traditionally been used since antiquity to treat various gastroenteritis and respiratory symptoms similar to COVID-19 outcomes. The common symptoms of COVID-19 include fever or chills, cold, cough, flu, headache, diarrhoea, tiredness/fatigue, sore throat, loss of taste or smell, asthma, shortness of breath, or difficulty breathing, etc. This study aims to find out the plants and plant-derived products which are being used by the COVID-19 infected patients in Bangladesh and how those plants are being used for the management of COVID-19 symptoms. In this study, online and partially in-person survey interviews were carried out among Bangladeshi respondents. We selected Bangladeshi COVID-19 patients who were detected Coronavirus positive (+) by RT-PCR nucleic acid test and later recovered. Furthermore, identified plant species from the surveys were thoroughly investigated for safety and efficacy based on the previous ethnomedicinal usage reports. Based on the published data, they were also reviewed for their significant potentialities as antiviral, anti-inflammatory, and immunomodulatory agents. We explored comprehensive information about a total of 26 plant species, belonging to 23 genera and 17 different botanical families, used in COVID-19 treatment as home remedies by the respondents. Most of the plants and plant-derived products were collected directly from the local marketplace. According to our survey results, greatly top 5 cited plant species measured as per the highest RFC value are Camellia sinensis (1.0) > Allium sativum (0.984) > Azadirachta indica (0.966) > Zingiber officinale (0.966) > Syzygium aromaticum (0.943). Previously published ethnomedicinal usage reports, antiviral, anti-inflammatory, and immunomodulatory activity of the concerned plant species also support our results. Thus, the survey and review analysis simultaneously reveals that these reported plants and plant-derived products might be promising candidates for the treatment of COVID-19. Moreover, this study clarifies the reported plants for their safety during COVID-19 management and thereby supporting them to include in any future pre-clinical and clinical investigation for developing herbal COVID-19 therapeutics.
Databáze: OpenAIRE
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