The association between Toll-like Receptor 4, CD14 and coronary atherosclerosis
| Autor: | Nikos Goutas, Maria Kalliopi Konstantinidou, Dimitrios Vlachodimitropoulos, Nikoleta Poumpouridou |
|---|---|
| Jazyk: | angličtina |
| Předmět: |
Pulmonary and Respiratory Medicine
Toll-like receptor Innate immune system business.industry CD14 General Medicine medicine.disease Bioinformatics Coronary artery disease Pathogenesis Immune system Meeting Abstract medicine TLR4 Surgery business Cardiology and Cardiovascular Medicine Coronary atherosclerosis |
| Zdroj: | Journal of Cardiothoracic Surgery |
| ISSN: | 1749-8090 |
| DOI: | 10.1186/1749-8090-10-s1-a273 |
| Popis: | Immune and inflammatory mechanisms are considered to play a key role in the pathogenesis of atherosclerosis. Toll-like-Receptor4 and CD14 receptors are involved in the intracellular signalling pathway of the innate immune and inflammatory responses against pathogens. Functional polymorphisms of TLR4 and CD14 have so far conflicting impact on coronary artery disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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