Synthesis of Quaternary alpha-Perfluoroalkyl Lactams via Electrophilic Perfluoroalkylation
| Autor: | Antonio Togni, Fabian Brüning, Bruno Commare, Dmitry Katayev, Jiri Vaclavik |
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| Rok vydání: | 2016 |
| Předmět: |
Hydrocarbons
Fluorinated Lactams Silylation Ketene 010402 general chemistry 01 natural sciences Catalysis chemistry.chemical_compound Materials Chemistry Organic chemistry Trifluoromethyl Molecular Structure 010405 organic chemistry Metals and Alloys Hypervalent molecule General Chemistry Ethylenes Ketones 0104 chemical sciences Surfaces Coatings and Films Electronic Optical and Magnetic Materials chemistry Reagent Electrophile Ceramics and Composites Indicators and Reagents Iodine |
| Zdroj: | Chem. Commun. Chemical Communications |
| DOI: | 10.1039/c6cc00700g |
| Popis: | Efficient protocols enabling the rapid installation of trifluoromethyl, as well as further functionalized fluoroalkyl groups by an electrophilic perfluoroalkylation of lactam-derived ketene silyl amides (KSAs) using hypervalent iodine reagents 1 and 2 have been developed. |
| Databáze: | OpenAIRE |
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