Significant response to oral Etoposide in the treatment of an unresectable cardiac sarcoma
| Autor: | Richard L. Tower, Chelsea L. Collins, Peter J. Bartz, David R. Lal, Annette D. Segura, Ronald K. Woods |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
Biopsy Administration Oral Article Heart Neoplasms medicine Adjuvant therapy Humans Cardiac sarcoma Child Etoposide medicine.diagnostic_test business.industry Remission Induction Sarcoma Hematology medicine.disease Antineoplastic Agents Phytogenic Surgery medicine.anatomical_structure Oncology Ventricle Pediatrics Perinatology and Child Health Significant response Female Oral etoposide business medicine.drug |
| Zdroj: | Journal of pediatric hematology/oncology. 36(4) |
| ISSN: | 1536-3678 |
| Popis: | Primary cardiac sarcomas are rare and carry a poor prognosis. The standard of care is complete resection. Outcomes for patients without complete resection are dismal, and the benefit of adjuvant therapy is uncertain. A 9-year-old female presented with a large right-sided cardiac mass. Following biopsy, the tumor was classified as an undifferentiated sarcoma. Resection was not feasible due to apparent invasion of the right ventricle and atrioventricular groove. Treatment with oral etoposide resulted in a 97% reduction in tumor volume and allowed for complete resection of residual tumor. She is alive with no evidence of disease 25 months from diagnosis. |
| Databáze: | OpenAIRE |
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