Adaptation to restricted intake of protein and energy
| Autor: | Khan Ma, Bender Ae |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
Male
medicine.medical_specialty Nitrogen balance Nitrogen Medicine (miscellaneous) chemistry.chemical_compound Weight loss Casein Internal medicine medicine Animals chemistry.chemical_classification Nutrition and Dietetics Methionine biology Arginase Body Weight Alanine Transaminase Adaptation Physiological Diet Rats Enzyme Endocrinology chemistry Alanine transaminase Liver Protein Biosynthesis biology.protein Dietary Proteins Adaptation medicine.symptom Energy Intake Energy Metabolism Food Deprivation |
| Zdroj: | Nutrition and metabolism. 23(6) |
| ISSN: | 0029-6678 |
| Popis: | Adult rats that maintained nitrogen balance on a diet containing 5% casein fed ad libitum were restricted to 70% of their normal food intake for 31 days. This resulted in a negative N balance, loss of body weight and increased activities of hepatic glutamic pyruvic transaminase and arginase – all of which persisted for 10 days. After this time there was no further weight loss, the negative N balance returned to equilibrium and the activities of the two enzymes returned to normal indicating adaptation to the dietary restriction. Radio-isotope studies with labelled methionine showed that dietary restriction led to an increase in the radioactivity of the liver and a decrease of that of the muscles indicating maintenance of liver protein at the expense of muscle protein. Resting oxygen consumption decreased by 34% after 20 days of dietary restriction and this would account for the adaptation observed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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