CD4 lymphocyte count in HIV-positive persons exposed to Cryptococcus neoformans
| Autor: | U. Futh, Gernot Grosse, K. Arasteh, F. Staib, M. L’age |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Cryptococcus neoformans
Adult Male biology AIDS-Related Opportunistic Infections Opportunistic infection Immunology Cryptococcus Cryptococcosis biology.organism_classification medicine.disease Virology CD4 Lymphocyte Count Acquired immunodeficiency syndrome (AIDS) medicine Humans Viral disease Sida Mycosis |
| Zdroj: | Zentralblatt fur Bakteriologie : international journal of medical microbiology. 283(1) |
| ISSN: | 0934-8840 |
| Popis: | Summary A report is presented on four HIV positive homosexual men examined after several months of exposure during cleaning of a flat from masses of pigeon droppings heavily colonized by Cryptococcus neoformans . Only one out of the four persons, with a CD4 lymphocyte count of 50/μ L, fell sick from systemic cryptococcosis, but not the others, with CD4 lymphocyte counts of 180, 250, and 630/μL, respectively; they remained clinically and mycologically inconspicuous and free from C. neoformans . Open questions in view of the epidemiology of opportunistic pathogens in AIDS are discussed with regard to the CD4 cell count as a parameter indicating a predisposition for cryptococcosis as an airborne AIDS-defining opportunistic infection. This has been confirmed by specific cultural diagnosis of the agent in both the environment and the patient. Already in 1987/88, the probable source of infection had been the subject of epidemiological studiPC nn C. neoformans in Berlin |
| Databáze: | OpenAIRE |
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