Measurement of magnetostimulation thresholds in the porcine heart

Autor: Valerie Klein, Jaume Coll‐Font, Livia Vendramini, Donald Straney, Mathias Davids, Natalie G. Ferris, Lothar R. Schad, David E. Sosnovik, Christopher T. Nguyen, Lawrence L. Wald, Bastien Guérin
Rok vydání: 2022
Předmět:
Zdroj: Magnetic Resonance in Medicine. 88:2242-2258
ISSN: 1522-2594
0740-3194
Popis: Powerful MRI gradient systems can surpass the International Electrotechnical Commission (IEC) 60601-2-33 limit for cardiac stimulation (CS), which was determined by simple electromagnetic simulations and electrode stimulation experiments. Only a few canine studies measured magnetically induced CS thresholds in vivo and extrapolating them to human safety limits can be challenging.We measured cardiac magnetostimulation thresholds in 10 healthy, anesthetized pigs using capacitors discharged into a flat spiral coil to produce damped sinusoidal waveforms with effective stimulus duration tThe average dB/dt threshold estimated in the porcine heart was 1.66 ± 0.23 kT/s, which is 11-fold greater than the IEC dB/dt limit at tThis first measurement of cardiac magnetostimulation thresholds in pigs indicates that the IEC cardiac safety limit is conservative for the investigated stimulus duration (t
Databáze: OpenAIRE
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