Whipple's disease orbitopathy: case report and review of literature
| Autor: | Rui A. Carvalho, Sara Pereira, Filipa Sampaio, Bruna Vieira, Jorge E. Moreira, Sofia Jordão |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Erythema Tropheryma Tropheryma whipplei 03 medical and health sciences 0302 clinical medicine medicine Humans Whipple's disease 030223 otorhinolaryngology Myositis biology business.industry Incidentaloma Hydroxychloroquine Middle Aged medicine.disease biology.organism_classification Anti-Bacterial Agents Graves Ophthalmopathy Ophthalmology Doxycycline 030221 ophthalmology & optometry Prednisolone Female Sarcoidosis Radiology medicine.symptom business Whipple Disease medicine.drug |
| Zdroj: | Orbit (Amsterdam, Netherlands). 41(1) |
| ISSN: | 1744-5108 |
| Popis: | A 59-year-old female patient was diagnosed with Whipple's disease (WD) after several months of constitutional complaints and adenopathies that were initially misinterpreted as sarcoidosis. Initial treatment included doxycycline, hydroxychloroquine and prednisolone, which was suspended due to long-term clinical stability. Four months after prednisolone suspension, the patient presented with right periorbital oedema and erythema. Ophthalmological examination revealed restricted eye movements. A computed tomography (CT) scan demonstrated signs of myositis. The patient was treated with anti-inflammatory and antibiotic drugs, that induced remission of the orbitopathy. During the following two years, she presented three relapses, affecting both the right or the left eyes. The last episode was also associated with systemic corticosteroid tapering. Orbitopathy is a rare form of WD presentation and the diagnosis of this condition may be challenging. As the clinical spectrum may range from an incidentaloma to a severe compressive neuropathy, proper recognition and management of WD orbitopathy is essential. |
| Databáze: | OpenAIRE |
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