CRYSTALLINE AGGREGATES OF PROTEIN-GLYCOGEN COMPLEXES (ALIAS ‘VIRUS-LIKE PARTICLES’) IN SKELETAL MUSCLE: REPORT OF A CASE AND REVIEW OF THE LITERATURE

Autor: S. Luh, L. Palmucci, A. P. Anzil
Rok vydání: 1983
Předmět:
Zdroj: Neuropathology and Applied Neurobiology. 9:61-71
ISSN: 1365-2990
0305-1846
DOI: 10.1111/j.1365-2990.1983.tb00324.x
Popis: Palmucci L., Anzil A.P. & Luh S. (1983) Neuropathology and Applied Neurobiology 9, 61–71 Crystalline aggregates of protein-glycogen complexes (alias ‘viruslike particles’) in skeletal muscle: report of a case and review of the literature Crystalline arrays of so-called ‘virus-like particles’ were found in postmortem samples of skeletal muscle obtained from an 11-month-old female infant. In a large number of skeletal muscle fibres crystalline inclusions were abundant, variously configurated and positively stained with a cytochemical method for polysaccharides. A battery of enzymatic tests, including some with diastase and a-amylase, was, however, entirely non-contributory. A muscle biopsy studied 5 months before death had disclosed no crystalline inclusions of any kind. The literature concerning similar cases of ‘virus-like particles’, crystalline glycogen aggregates or protein-glycogen complexes in muscle is reviewed. Possible reasons underlying the aggregation of protein-glycogen complexes into crystalline arrays are discussed.
Databáze: OpenAIRE