A study of the phase-transfer alkoxycarbonylation of secondary alkyl amines. Application of a factorial design

Autor:	Félix Sánchez, Tomás Torres, Vicente Gómez-Parra
Rok vydání:	1987
Předmět:	chemistry.chemical_classification Carbamate Tertiary amine medicine.medical_treatment Factorial experiment Alkylation Potassium carbonate chemistry.chemical_compound chemistry medicine Organic chemistry Solvent effects Aliphatic compound Alkyl
Zdroj:	Scopus-Elsevier
ISSN:	1364-5471 0300-9580
DOI:	10.1039/p29870000695
Popis:	A 24 factorial design has been applied to the study of the competitive alkylation versus alkoxycarbonylation of secondary alkyl amines under phase-transfer conditions. The relative influence of the experimental variables and their interactions in the course of the reaction have been rationalized. The optimal conditions to obtain high carbamate yields have been established and experimentally corroborated.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c9d2d2965a8a2a4aab8515ffb8bbbce https://doi.org/10.1039/p29870000695 Zobrazit plný text záznamu