Antibiotic Resistant Bacterial Isolates from Captive Green Turtles andIn VitroSensitivity to Bacteriophages
| Autor: | Jacqueline Picard, Alessandro Delli Paoli Carini, Ellen Ariel, Lisa Elliott |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Article Subject medicine.drug_class 030106 microbiology Antibiotics Broth microdilution Biology Amoxicillin Microbiology QR1-502 Multiple drug resistance 03 medical and health sciences Antibiotic resistance Clavulanic acid Ampicillin medicine Ceftiofur medicine.drug |
| Zdroj: | International Journal of Microbiology, Vol 2017 (2017) |
| ISSN: | 1687-9198 1687-918X |
| DOI: | 10.1155/2017/5798161 |
| Popis: | This study aimed to test multidrug resistant isolates from hospitalised green turtles(Chelonia mydas)and their environment in North Queensland, Australia, forin vitrosusceptibility to bacteriophages. Seventy-one Gram-negative bacteria were isolated from green turtle eye swabs and water samples. Broth microdilution tests were used to determine antibiotic susceptibility. All isolates were resistant to at least two antibiotics, with 24% being resistant to seven of the eight antibiotics. Highest resistance rates were detected to enrofloxacin (77%) and ampicillin (69.2%). More than 50% resistance was also found to amoxicillin/clavulanic acid (62.5%), ceftiofur (53.8%), and erythromycin (53.3%). All the enriched phage filtrate mixtures resulted in the lysis of one or more of the multidrug resistant bacteria, includingVibrio harveyiandV. parahaemolyticus. These results indicate that antibiotic resistance is common in Gram-negative bacteria isolated from hospitalised sea turtles and their marine environment in North Queensland, supporting global concern over the rapid evolution of multidrug resistant genes in the environment. Using virulent bacteriophages as antibiotic alternatives would not only be beneficial to turtle health but also prevent further addition of multidrug resistant genes to coastal waters. |
| Databáze: | OpenAIRE |
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