Can dentists detect multiple myeloma through oral manifestations?

Autor: Roberto José Pessoa Magalhães, Sandra Torres, Alessandra da Silva Freitas, Édila Figuerêdo Feitosa Cavalcanti, Thaís Miranda Xavier de Almeida, Angelo Maiolino
Rok vydání: 2017
Předmět:
Zdroj: Hematology, Transfusion and Cell Therapy, Vol 40, Iss 1, Pp 43-49 (2018)
Hematology, Transfusion and Cell Therapy, Volume: 40, Issue: 1, Pages: 43-49, Published: MAR 2018
ISSN: 1516-8484
Popis: Objective: To review published data on oral manifestations of multiple myeloma. Methods: An electronic database search was performed of articles published from 1971 to November 2016 in order to identify studies that reported oral manifestations of patients with multiple myeloma. Case reports and case series with oral manifestations of multiple myeloma in English were included in the study. An additional search was performed of the references of the selected articles. Results: Thirty-seven articles that reported 81 patients with oral manifestations of multiple myeloma were selected: 30 case reports (82%) and seven case series (18%). The most common clinical features in the dental cavity were swelling (65.4%), bone pain (33.3%), paresthesia (27.1%) and amyloidosis lesions (11.1%). Osteolytic lesions detected on imaging exams were reported in the majority of the patients (90.1%) as plasmacytomas or ‘punched-out’ lesions. Conclusions: Swelling and osteolytic lesions represent the most common clinical and radiographic signs of the jaws relating to multiple myeloma, respectively. Keywords: Multiple Myeloma, Oral Manifestations, Mouth, Jaws
Databáze: OpenAIRE