Developments in surgical oncology — past, present and future trends

Autor: S B Renwick, Lex Watson, W H McCarthy, J M Bell, F. O. Stephens, John F. Thompson, D W Storey, F W Niesche, F W Marsden
Rok vydání: 1991
Předmět:
Zdroj: Medical Journal of Australia. 155:803-807
ISSN: 1326-5377
0025-729X
DOI: 10.5694/j.1326-5377.1991.tb94042.x
Popis: The historical development of integrated treatment programs for locally advanced or aggressive cancers, for which the results of surgical excision or radiotherapy are unsatisfactory, is reviewed. Chemotherapy should be used first (induction chemotherapy), while tumour vasculature is intact; intra-arterial infusion gives a greater regional effect. Central residual tumour may be eradicated by subsequent radiotherapy and/or surgery. Regional induction chemotherapy is particularly useful in treating locally advanced stage III breast cancer, locally advanced head and neck cancer, gastric cancer, and locally advanced sarcomas and melanomas of the limbs. A team approach, involving surgical and medical oncologists, radiotherapists, immunologists, and others should improve the results in these patients.
Databáze: OpenAIRE