Evidence that ‘Inactive’ Renin is Produced outside the Kidney of the Rat
| Autor: | K. D. Strang, Marianne Poessée, W. H. Birkenhager, R. Vandongen |
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| Rok vydání: | 1977 |
| Předmět: |
Male
medicine.medical_specialty Kidney Chemistry Peripheral plasma Rat kidney Stimulation General Medicine Hydrogen-Ion Concentration In Vitro Techniques Rats Inactive renin Enzyme Activation Endocrinology medicine.anatomical_structure Internal medicine Isoprenaline Renin Renin–angiotensin system medicine Animals medicine.drug |
| Zdroj: | Clinical Science. 53:189-191 |
| ISSN: | 0301-0538 |
| DOI: | 10.1042/cs0530189 |
| Popis: | 1. Inactive renin, which can be converted into an active form by acidification to pH 3·3, represents 4–63% of the total renin in rat peripheral plasma. 2. No inactive component could be found in the blood-free venous effluent of the perfused rat kidney before and after stimulation with isoprenaline. 3. This suggests a possible extrarenal source for inactive renin and may explain the presence of this component in anephric patients. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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