EPR study of anion radicals of various N-quinonyl amino acids
| Autor: | Alexander I. Shames, Evgenia Lozinsky, S. Bittner, S. Gorohovsky |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
chemistry.chemical_classification
Chemical structure Organic Chemistry Clinical Biochemistry Electron Spin Resonance Spectroscopy Quinones Anion radicals Peptide Photochemistry Biochemistry Medicinal chemistry law.invention Adduct Amino acid chemistry law Computer Simulation Amino Acids Electron paramagnetic resonance Oxidation-Reduction |
| Zdroj: | Amino Acids. 19:439-449 |
| ISSN: | 1438-2199 0939-4451 |
| DOI: | 10.1007/s007260070022 |
| Popis: | Since peptide quinones possess great clinical potential in targeted chemotherapy, several series of novel N-quinonyl amino acids have been synthesized and their first products of reduction were studied by EPR spectroscopy. EPR spectra of the corresponding radical adducts were identified by computer simulation. The dependence between the splitting constants and the chemical structure of the N-quinonyl amino acids anion radicals was examined. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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