The influence of diabetes and prediabetes on left heart remodeling: A population-based study
| Autor: | Tan Li, GuangXiao Li, Xiaofan Guo, Zhao Li, Yingxian Sun, Jun Yang |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty China Endocrinology Diabetes and Metabolism Population Diastole 030209 endocrinology & metabolism 030204 cardiovascular system & hematology Left ventricular hypertrophy Prediabetic State 03 medical and health sciences 0302 clinical medicine Endocrinology Risk Factors Diabetes mellitus Internal medicine Internal Medicine medicine Left atrial enlargement Diabetes Mellitus Humans cardiovascular diseases Prediabetes Heart Atria Prospective Studies Risk factor education Prospective cohort study education.field_of_study Ventricular Remodeling business.industry medicine.disease Glucose Cardiology Female Hypertrophy Left Ventricular business |
| Zdroj: | Journal of diabetes and its complications. 35(2) |
| ISSN: | 1873-460X |
| Popis: | Background Diabetes was regarded as an independent risk factor for abnormal left heart remodeling. However, there was lacking population-based data on the relationship of glucose status with left ventricular hypertrophy (LVH) or left atrial enlargement (LAE). This study intended to clarify the influence of diabetes and prediabetes on the prevalence and incidence of LVH and LAE based on a northeast rural population of China. Methods We analyzed clinical, laboratory and echocardiographic data of a total of 2824 participants aged over 35 years from a population-based prospective cohort NCRCHS study with 2 years of follow-up, which was carried out in rural areas of northeast China. All measurements were performed according to standardized protocols. Results There were 2179 controls, 342 subjects with prediabetes and 303 ones with diabetes. The baseline distribution of LAD, IVSd, LVIDd, LVIDs, LVMI, E wave, A wave, E/A, E/e′, diastolic dysfunction, LVEDV, LVESV and SV was significantly different among three groups (all Ptrend Conclusion Diabetes, but not prediabetes, is an independent predictor for the prevalence of LVH and LAE, and for the new-onset LAE, it should be considered in the assessment of diabetes and cardiac structural remodeling. |
| Databáze: | OpenAIRE |
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