Release of secretin--plasma levels reproduced by exogenous infusion

Autor:	J. Marjason, L. Lazarus, L. Henderson, D. J. Byrnes
Rok vydání:	1979
Předmět:	medicine.medical_specialty Gastric Juice business.industry Duodenum Radioimmunoassay Proteins Plasma levels Secretin Peak plasma Endocrinology medicine.anatomical_structure Glucose Internal medicine Internal Medicine medicine Humans Secretion Infusions Parenteral business
Zdroj:	Australian and New Zealand journal of medicine. 9(2)
ISSN:	0004-8291
Popis:	Infusion of 0.1 M HCl (0.5 mmol/kg/hr over 20 minutes) into the duodenum of each of seven normal subjects led to a significant rise (P less than 0.05) in mean plasma secretion levels from 3.0 +/- 2.2 (SE) to 15 +/- 4.0 pmol/l. Intravenous infusion of secretin at a rate of 6.6 pmol/kg/hr (0.08 clinical units/kg/hr) reproduced the peak plasma levels of secretin observed during duodenal acidification. However, there was no detectable (2.5 pmol/l) change in plasma secretin after oral protein or glucose.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c778a303371f1992c0d4489014fc6e6 https://pubmed.ncbi.nlm.nih.gov/287456 Zobrazit plný text záznamu Plný text