Structural Studies of H-2 and TL Alloantigens
| Autor: | Ellen S. Vitetta, J D Capra, Miroslav D. Poulik, D. G. Klapper, J. W. Uhr, Jan Klein |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Isoantigens
Stereochemistry T-Lymphocytes Beta-Globulins Immunoglobulin Variable Region Immunoglobulin domain Biology Biochemistry Homology (biology) Mice Histocompatibility Antigens Genetics Animals Amino Acid Sequence Allele Molecular Biology Haplotype Protein primary structure TL-antigens Immunology biology.protein Free form Antibody Immunoglobulin Heavy Chains beta 2-Microglobulin Spleen |
| Zdroj: | Cold Spring Harbor Symposia on Quantitative Biology. 41:363-368 |
| ISSN: | 1943-4456 0091-7451 |
| DOI: | 10.1101/sqb.1977.041.01.043 |
| Popis: | Questions concerning the association of ..beta..-2-microglobulin (..beta../sub 2/m) with H-2 and TL antigens on the cell surface or the existence of ..beta../sub 2/m in the free form and associated with many other molecules were investigated. If there is a large excess of free ..beta../sub 2/m it could be argued that the association with H-2 is fortuitous and occurs during the isolation procedure or during capping. Studies were also conducted on the partial primary structure of two H-2K haplotypes in relation to their being alleles and homology between H-2K and immunoglobulin domains. (HLW) |
| Databáze: | OpenAIRE |
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