HLA-A, -B and -DRB1 genotyping and haplotype frequencies of 3892 cord blood units in the Hong Kong Chinese Cord Blood Registry
| Autor: | Mengbiao Guo, Janette Kwok, Jenny C. Y. Ho, N.K. Chan, Godfrey Chi-Fung Chan, Liwei Lu, Wanling Yang, Derek Middleton, Cheuk-Kwong Lee, WH Tang, Y.S. Chan |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Genotype medicine.medical_treatment Immunology Population Hematopoietic stem cell transplantation 03 medical and health sciences 0302 clinical medicine Asian People Gene Frequency Internal medicine Humans Immunology and Allergy Medicine Registries education Allele frequency Genotyping Genetics education.field_of_study HLA-A Antigens business.industry Histocompatibility Testing Haplotype Hematopoietic Stem Cell Transplantation General Medicine Fetal Blood HLA-A Transplantation Genetics Population 030104 developmental biology Haplotypes HLA-B Antigens Cord blood Blood Banks Hong Kong business HLA-DRB1 Chains 030215 immunology |
| Zdroj: | Human Immunology. 77:1109-1110 |
| ISSN: | 0198-8859 |
| Popis: | HLA-A, -B and -DRB1 gene and haplotype frequencies have been calculated from 3892 southern Chinese unrelated cord blood units in a Hong Kong Cord Blood Registry. This is the first large-scale paper to report the distribution of A-B-DRB1 alleles in Hong Kong Chinese Cord Blood Units. This information is important for estimating the optimal and economically cost-effective donor size and likelihood of obtaining appropriately matched cord blood units for Chinese patients awaiting haematopoietic stem cell transplantation. The data are available in the Allele Frequencies Net Database under the population name ''Hong Kong Chinese Cord Blood Registry'' and the identifier (AFND003358). |
| Databáze: | OpenAIRE |
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