Self-Reported Hypoglycemia in Insulin-Treated Patients with Diabetes: Results from the Philippine Cohort of the International Operations Hypoglycemia Assessment Tool (IO HAT) Study
| Autor: | Nemencio A. Nicodemus, Susan Yu-Gan, Roberto Mirasol, Arvind Vilas Gadekar, Anand B. Jain |
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| Rok vydání: | 2017 |
| Předmět: |
Type 1 diabetes
Pediatrics medicine.medical_specialty endocrine system diseases business.industry International Operations Hypoglycemia Assessment Tool Endocrinology Diabetes and Metabolism Insulin medicine.medical_treatment Incidence (epidemiology) Philippines Type 2 Diabetes Mellitus nutritional and metabolic diseases Hypoglycemia medicine.disease insulin-treated patients with diabetes Endocrinology hypoglycemia Diabetes mellitus Cohort medicine Original Article business Patient education |
| Zdroj: | Journal of the ASEAN Federation of Endocrine Societies |
| ISSN: | 0857-1074 |
| Popis: | Objective. To determine the frequency of hypoglycemia in insulin-treated patients with type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) in the non-interventional International Operations Hypoglycemia Assessment Tool (IO HAT) study. Methodology. This sub-analysis included Filipino patients with T1DM or T2DM, aged 18 years and older, treated with insulin for more than 12 months, who completed the two-part self-assessment questionnaires (SAQ1 and SAQ2) and patient diaries that recorded hypoglycemia during retrospective (6 months/4 weeks before baseline) and prospective period (4 weeks after baseline) (ClinicalTrials.gov number: NCT02306681). Results. A total of 671 patients were enrolled and completed the SAQ1 (62 patients with T1DM and 609 patients with T2DM). Almost all patients (100% in T1DM and 99.3% in T2DM) experienced at least 1 hypoglycemic event prospectively. The incidence of any hypoglycemia was also high in the prospective period compared to retrospective period (72.6 [95% CI: 64.8, 80.9] events PPY and 43.6 [95% CI: 37.8, 49.9] events PPY; p=0.001, respectively) in T1DM patients. Conclusion. Among insulin-treated patients, higher rates of hypoglycemia were reported prospectively than retrospectively. This indicates that the patients in real-life setting often under report hypoglycemia. Patient education can help in accurate reporting and appropriate management of hypoglycemia and diabetes. |
| Databáze: | OpenAIRE |
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