Usefulness of Muscle Synergy Analysis in Individuals With Knee Osteoarthritis During Gait
| Autor: | Hiroki Hanawa, Tsutomu Fujino, Keisuke Hirata, Shunsuke Kita, Keisuke Kubota, Moeka Yokoyama, Naohiko Kanemura, T. Ishibashi, Takanori Kokubun |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Knee Joint Biomedical Engineering Osteoarthritis Electromyography 03 medical and health sciences Joint disease 0302 clinical medicine Physical medicine and rehabilitation Internal Medicine medicine Humans Treadmill Muscle synergy Gait Aged medicine.diagnostic_test Stance phase business.industry General Neuroscience Muscles Rehabilitation 030229 sport sciences Osteoarthritis Knee medicine.disease Biomechanical Phenomena Biomarker (medicine) business 030217 neurology & neurosurgery |
| Zdroj: | IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society. 29 |
| ISSN: | 1558-0210 |
| Popis: | Objective: To clarify whether there are any muscle synergy changes in individuals with knee osteoarthritis, and to determine whether muscle synergy analysis could be applied to other musculoskeletal diseases. Methods: Subjects in this study included 11 young controls (YC), 10 elderly controls (EC), and 10 knee osteoarthritis patients (KOA). Gait was assessed on a split-belt treadmill at 3 km/h. A non-negative matrix factorization (NNMF) was applied to the electromyogram data matrix to extract muscle synergies. To assess the similarity of each module, we performed the NNMF analysis assuming four modules for all of the participants. Further, we calculated joint angles to compare the kinematic data between the module groups. Results: The number of muscle modules was significantly lower in the EC (2–3) and KOA (2–3) groups than in the YC group (3–4), which reflects the merging of late swing and early stance modules. The EC and KOA groups also showed greater knee flexion angles in the early stance phase. Contrarily, by focusing on the module structure, we found that the merging of early and late stance modules is characteristic in KOA. Conclusion: The lower number of modules in the EC and KOA groups was due to the muscle co-contraction with increased knee flexion angle. Contrarily, the merging of early and late stance modules are modular structures specific to KOA and may be biomarkers for detecting KOA. Significance: Describing the changes in multiple muscle control associated with musculoskeletal degeneration can serve as a fundamental biomarker in joint disease. |
| Databáze: | OpenAIRE |
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