Health Hazards in Middle-Aged Women with Cardiovascular Disease: A Case-Control Study of Swedish Women. The Women's Health in the Lund Area (WHILA) Study
| Autor: | Christina Nerbrand, Per Nyberg, Jonas Lidfeldt, Yasameen A. Shakir, Göran Samsioe, Carl-David Agardh, Ali Khatibi E |
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| Rok vydání: | 2007 |
| Předmět: |
medicine.medical_specialty
Waist Health Status Urinary incontinence Irritability Risk Assessment Body Mass Index Risk Factors Surveys and Questionnaires Diabetes mellitus Internal medicine Activities of Daily Living Prevalence medicine Humans Obesity Myocardial infarction Sweden business.industry Cholesterol HDL Smoking Case-control study Cholesterol LDL General Medicine Middle Aged medicine.disease Lipids Hormones Postmenopause Blood pressure Cardiovascular Diseases Case-Control Studies Body Composition Quality of Life Physical therapy Women's Health Female medicine.symptom business Body mass index Stress Psychological |
| Zdroj: | Journal of Women's Health. 16:406-414 |
| ISSN: | 1931-843X 1540-9996 |
| DOI: | 10.1089/jwh.2006.0056 |
| Popis: | Objective: To delineate the health profile in middle-aged women with cardiovascular disease (CVD). Methods: The Women's Health in the Lund Area (WHILA) project covered all women born 1935 - 1945 ( n = 10,766) living in the Lund area; 6917 (64.2%) women completed a generic questionnaire and underwent physical and laboratory assessments. Of the 6917 women, 6416 were postmenopausal women, of whom 104 had CVD. For each woman with CVD, two controls were selected and matched for age, smoking habits, body mass index (BMI), waist/hip ratio (WHR), low-density lipoprotein cholesterol (LDL-C), high-density liproprotein cholesterol (HDL-C), diastolic blood pressure and hormonal status. Results: One hundred four women (1.6%) reported CVD. Forty-nine had a myocardial infarction (MI), 49 had a stroke, and 6 women had both events; 71.4% were postmenopausal, with never use of hormone therapy ( HT) ( PM0), and 28.6% were postmenopausal with ever use of HT (PMT). Compared with the control group, serum androstendione was lower ( p = 0.004) in the case group, and menopausal estradiol (E-2) values were less frequent ( p = 0.037) in cases from the PM0 group. Among psychological and somatic symptoms, nervousness ( p < 0.05), difficulty relaxing, crying easily, visual disturbance ( p |
| Databáze: | OpenAIRE |
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