C-reactive protein in childhood meningitides
| Autor: | K. M. Belapurkar, Kamlesh Harish, Y. P. Thawrani, S. Shrivastava, Harish K Pemde |
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| Rok vydání: | 1996 |
| Předmět: |
Meningitides
Male medicine.medical_specialty Gastroenterology Sensitivity and Specificity Tuberculous meningitis Central nervous system disease Diagnosis Differential Cerebrospinal fluid Internal medicine medicine Humans Meningitis Child biology business.industry Meningitis Pneumococcal C-reactive protein Infant medicine.disease Latex fixation test C-Reactive Protein Child Preschool Tuberculosis Meningeal Pediatrics Perinatology and Child Health Immunology biology.protein Female Differential diagnosis business Biomarkers Latex Fixation Tests |
| Zdroj: | Indian journal of pediatrics. 63(1) |
| ISSN: | 0019-5456 |
| Popis: | Utility of C-reactive protein (CRP) latex agglutination test in meningitis was evaluated. Serum CRP test was positive in 100% cases of meningitic groups and 53% cases of “no meaningitis (NM)” group. Cerebrospinal fluid (CSF) CRP test was positive in 100% cases of pyogenic meningitis, whereas it was negative in 95% cases of tuberculous meningitis and 100% cases of NM group. CSF CRP test showed 100% sensitivity and negativbe predictive values, 95–100% specificity and 94–100% positive predictive values for various inter-group differentiations. This study conclluded that CSF CRP positive cases should be considered as pyogenic meningitis unless proved otherwise. Routine use of this simple, reliable and inexpensive test is recommended for rapid diagnosis and differential diagnosis f meningitis. |
| Databáze: | OpenAIRE |
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