Reconstruction of Chronic Wounds Secondary to Injectable Drug Use with a Biodegradable Temporizing Matrix
| Autor: | David J. Rowe, James Gatherwright, Grzegorz Kwiecien, Christopher Cheng, Kyle J. Chepla |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Drug
medicine.medical_specialty Debridement medicine.diagnostic_test RD1-811 business.industry medicine.medical_treatment media_common.quotation_subject Osteomyelitis Treatment options Case Report medicine.disease Surgery medicine.anatomical_structure Forearm Concomitant Biopsy medicine Skin grafting business Hand/Peripheral Nerve media_common |
| Zdroj: | Plastic and Reconstructive Surgery, Global Open, Vol 9, Iss 7, p e3678 (2021) Plastic and Reconstructive Surgery Global Open |
| ISSN: | 2169-7574 |
| DOI: | 10.1097/GOX.0000000000003678 |
| Popis: | Summary:. Injectable drug use in the upper extremity often leads to chronic wounds complicated by osteomyelitis. Conventional reconstructive options are often not feasible and/or are contraindicated in this patient population. We have started using a synthetic, biodegradable temporizing matrix (BTM) for the treatment of these patients. We hypothesize that BTM is a safe, low-risk, and low-morbidity alternative reconstructive option. We report outcomes after staged debridement and BTM application followed by split-thickness skin grafting for two patients with large, chronic bilateral forearm wounds with concomitant osteomyelitis confirmed by MRI and biopsy. No acute surgical complications were encountered and at a mean follow-up of 13 months, both patients had maintained stable soft-tissue coverage. Reconstruction using BTM is a novel treatment option that can simplify the reconstruction, reduce donor-site morbidity, and optimize success for patients with chronic wounds resulting from injectable drug use. Initial outcomes are promising; however, further comparative studies are needed to better evaluate long-term outcomes of this technique. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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