Role of PlGF in CNV
Autor: | Reichhart, N, Crespo-Garcia, S, Kociok, N, Joussen, AM, Strauß, O |
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Jazyk: | angličtina |
Rok vydání: | 2015 |
Předmět: | |
Zdroj: | VI. International Symposium on AMD-Age-Related Macular Degeneration-Emerging Concepts-Exploring known and Identifying new Pathways; 20150911-20150912; Baden-Baden; DOC15amd42 /20151001/ |
DOI: | 10.3205/15amd42 |
Popis: | Loss of vision in AMD is mainly due to the development of choroidal neovascularization (CNV), which is partly driven by macrophages and microglia that both carry VEGFR1 (flt-1) receptors specific for VEGF-A and PlGF. A switch from a pure anti- VEGF-A to an anti-PLGF+VEGF-A treatment is beneficial[for full text, please go to the a.m. URL] VI. International Symposium on AMD – Age-Related Macular Degeneration – Emerging Concepts – Exploring known and Identifying new Pathways |
Databáze: | OpenAIRE |
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