Resolution of necrolytic migratory erythema with somatostatin analogue in a patient diagnosed with pancreatic glucagonoma
| Autor: | Angela Lamarca, Cristina Saavedra, Richard A Hubner |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Male medicine.medical_specialty Constitutional symptoms Necrolytic Migratory Erythema Glucagonoma Glucagon Injections 03 medical and health sciences 0302 clinical medicine Pancreatic cancer medicine Humans Aged business.industry General Medicine Necrolytic migratory erythema medicine.disease Dermatology Rash Reminder of Important Clinical Lesson Pancreatic Neoplasms Neuroendocrine Tumors 030104 developmental biology medicine.anatomical_structure 030220 oncology & carcinogenesis Pancreatic Glucagonoma medicine.symptom business Pancreas Somatostatin |
| Zdroj: | BMJ Case Rep |
| Popis: | A 70-year-old man reported progressive weight loss, fatigue and a generalised rash. The rash was consistent with necrolytic migratory erythema, further investigations were performed and the patient was diagnosed with a mass in the tail of the pancreas, in keeping with a localised glucagonoma. Somatostatin analogue therapy was started for symptom control, leading to complete resolution of the skin rash and an improvement in constitutional symptoms. Subsequently, the pancreatic lesion was excised, and pathology assessment confirmed the diagnosis of well-differentiated neuroendocrine tumour with high expression of glucagon compatible with glucagonoma. |
| Databáze: | OpenAIRE |
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