Radiation therapy in operable breast cancer: results from the Stockholm trial on adjuvant radiotherapy
| Autor: | Per-Ola Granberg, Bertil Blomstedt, Jan Bergström, Ored Arner, Arne Wallgren, Claes Silfverswäd, Jerzy Einhorn, Lars Räf |
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| Rok vydání: | 1986 |
| Předmět: |
Cancer Research
medicine.medical_specialty medicine.medical_treatment Breast Neoplasms Modified Radical Mastectomy law.invention Random Allocation Breast cancer Randomized controlled trial law Adjuvant therapy medicine Humans Radiology Nuclear Medicine and imaging Stage (cooking) Neoplasm Metastasis Mastectomy Aged Adjuvant radiotherapy Clinical Trials as Topic Radiation business.industry Middle Aged medicine.disease Prognosis Combined Modality Therapy Surgery Supraclavicular lymph nodes Radiation therapy medicine.anatomical_structure Oncology Female Neoplasm Recurrence Local business Follow-Up Studies |
| Zdroj: | International journal of radiation oncology, biology, physics. 12(4) |
| ISSN: | 0360-3016 |
| Popis: | In a randomized trial, 960 women with Stage 1–3 operable breast cancer were treated by a modified radical mastectomy alone, or by the same procedure, preceded or followed by radiotherapy (4500 rad to the breast/chest wall, and internal mammary, axillary and supraclavicular lymph nodes). Up to ten years after treatment, there is an increasing gap between the recurrence-free survival of the irradiated patients and the surgical controls. Between the two types of radiotherapy, there was no difference. There were significantly fewer distant metastases and a tendency for improved survival in node positive patients treated with postoperative radiotherapy, compared to the surgical controls, this difference was, however, statistically not significant. |
| Databáze: | OpenAIRE |
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