Inverse Association of H2O2-Producing Lactobacilli and Vaginal Escherichia coli Colonization in Women with Recurrent Urinary Tract Infections
| Autor: | Ann E. Stapleton, Thomas M. Hooton, Kalpana Gupta, Cynthia L. Fennell, Walter E. Stamm, Pacita L. Roberts |
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| Rok vydání: | 1998 |
| Předmět: |
Adult
Urinary system Spermatocidal Agents medicine.disease_cause Microbiology Pathogenesis Recurrence Lactobacillus Escherichia coli medicine Humans Immunology and Allergy Colonization biology Spermicide Hydrogen Peroxide biology.organism_classification Enterobacteriaceae Infectious Diseases medicine.anatomical_structure Case-Control Studies Urinary Tract Infections Vagina Female |
| Zdroj: | Journal of Infectious Diseases. 178:446-450 |
| ISSN: | 1537-6613 0022-1899 |
| DOI: | 10.1086/515635 |
| Popis: | Women with recurrent urinary tract infection (UTI) often demonstrate persistent vaginal colonization with Escherichia coli. Since strains of lactobacilli that produce hydrogen peroxide inhibit the growth of E. coli, the absence of these strains may predispose to E. coli colonization and to UTI. To test this hypothesis, vaginal introital cultures were obtained from 140 women, 65 with recurrent UTI (case-patients) and 75 without (controls). Vaginal E. coli colonization was significantly more frequent in case-patients than controls (35% vs. 11%; P |
| Databáze: | OpenAIRE |
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