Selective inhibition of mammalian lanosterol 14 alpha-demethylase: a possible strategy for cholesterol lowering
| Autor: | K A, Walker, D J, Kertesz, D M, Rotstein, D C, Swinney, P W, Berry, O Y, So, A S, Webb, D M, Watson, A Y, Mak, P M, Burton |
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| Rok vydání: | 1993 |
| Předmět: |
Stereochemistry
Hamster Selective inhibition Sulfides Sterol 14-Demethylase Structure-Activity Relationship In vivo Cricetinae Drug Discovery Lanosterol 14 alpha-demethylase Animals Cytochrome P-450 Enzyme Inhibitors Humans Enzyme Inhibitors Aniline Compounds Chemistry Anticholesteremic Agents Absolute configuration Diastereomer Cholesterol lowering Biological activity Stereoisomerism Rats Cholesterol Biochemistry Molecular Medicine Oxidoreductases |
| Zdroj: | Journal of medicinal chemistry. 36(15) |
| ISSN: | 0022-2623 |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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