| Autor: |
David Chirio, Elisa Demonchy, Marion Le Marechal, Alice Gaudart, Romain Lotte, Michel Carles, Raymond Ruimy |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Clinical chemistry and laboratory medicineReferences. 61(2) |
| ISSN: |
1437-4331 |
| Popis: |
Objectives We aimed to evaluate the impact of an uninterrupted workflow regarding blood cultures on turnaround time and antibiotic prescription. Methods Monomicrobial episodes of bacteremia were retrospectively evaluated before and after a continuous 24/7 workflow was implemented in our clinical microbiology laboratory (pre- and post-intervention periods; PREIP and POSTIP). Primary outcome was the time from specimen collection to the first change in antibiotic therapy. Secondary outcomes included the time from specimen collection to effective antibiotic therapy and to antibiotic susceptibility testing results (or turnaround time), as well as hospital length of stay and all-cause mortality at 30 days. Results A total of 548 episodes of bacteremia were included in the final analysis. There was no difference in PREIP and POSTIP regarding patient characteristics and causative bacteria. In POSTIP, the mean time to the first change in antibiotic therapy was reduced by 10.4 h (p Conclusions Around the clock processing of blood cultures allows for a reduction in turnaround time, which in turn reduces the delay until effective antibiotic therapy prescription. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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