Association between fetal sex, birthweight percentile and adverse pregnancy outcome
| Autor: | Bart Jan Voskamp, Wessel Ganzevoort, Eva Pajkrt, Ben W.J. Mol, Myrthe J.C.S. Peelen, Robin van der Lee, Anita C.J. Ravelli, Brenda M. Kazemier |
|---|---|
| Přispěvatelé: | Amsterdam Reproduction & Development (AR&D), Graduate School, Obstetrics and Gynaecology, ARD - Amsterdam Reproduction and Development, Medical Informatics, APH - Quality of Care, APH - Personalized Medicine, APH - Health Behaviors & Chronic Diseases, APH - Methodology, APH - Digital Health |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty adverse outcome Perinatal Death Infant Newborn Diseases 03 medical and health sciences small for gestational age Sex Factors 0302 clinical medicine Meconium Pregnancy Risk Factors Infant Mortality medicine Birth Weight Humans sex Original Research Article Registries 030212 general & internal medicine reproductive and urinary physiology Netherlands antepartum death Fetus neonatal death 030219 obstetrics & reproductive medicine Respiratory distress Obstetrics business.industry intrapartum death Infant Newborn Pregnancy Outcome Infant Obstetrics and Gynecology Gestational age General Medicine medicine.disease 3. Good health Apgar Score Gestation Small for gestational age Female Apgar score business |
| Zdroj: | Acta Obstetricia et Gynecologica Scandinavica. Wiley-Blackwell Acta Obstetricia et Gynecologica Scandinavica Acta obstetricia et gynecologica Scandinavica, 99(1), 48-58. Wiley-Blackwell |
| ISSN: | 0001-6349 |
| Popis: | Introduction The objective was to evaluate the association between fetal sex and adverse pregnancy outcome, while correcting for fetal growth and gestational age at delivery. Material and methods Data from the Netherlands Perinatal Registry (1999‐2010) were used. The study population comprised all white European women with a singleton delivery between 25+0 and 42+6 weeks of gestation. Fetuses with structural or chromosomal abnormalities were excluded. Outcomes were antepartum death, intrapartum/neonatal death (from onset of labor until 28 days after birth), perinatal death (antepartum death or intrapartum/neonatal death), a composite of neonatal morbidity (including infant respiratory distress syndrome, sepsis, necrotizing enterocolitis, meconium aspiration, persistent pulmonary hypertension of the newborn, periventricular leukomalacia, Apgar score p90 [large for gestation]) and gestational age at delivery (25+0‐27+6, 28+0‐31+6, 32+0‐36+6, 37+0‐42+6 weeks). The association between fetal sex and outcome was assessed using the fetus at risk approach. Results We studied 1 742 831 pregnant women. We found no increased risk of antepartum, intrapartum/neonatal and perinatal death in normal weight and large‐for‐gestation males born after 28+0 weeks compared with females. We found an increased risk of antepartum death among small‐for‐gestation males born after 28+0 weeks (relative risk [RR] 1.16‐1.40). All males born after 32+0 weeks of gestation suffered more neonatal morbidity than females regardless of birthweight percentile (RR 1.07‐1.34). Infant respiratory distress syndrome, sepsis, persistent pulmonary hypertension of the newborn, Apgar score |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|