Outcomes of donation after circulatory death kidneys undergoing hypothermic machine perfusion following static cold storage: A UK population-based cohort study
| Autor: | James Hodson, Kamlesh Patel, Andrew R. Ready, Jay Nath, Nicholas Inston |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
medicine.medical_specialty Tissue and Organ Procurement animal structures 030232 urology & nephrology Urology Delayed Graft Function Cold storage 030230 surgery 03 medical and health sciences chemistry.chemical_compound Population based cohort 0302 clinical medicine medicine Humans Immunology and Allergy Pharmacology (medical) Transplantation Creatinine Machine perfusion business.industry Cold Ischemia Graft Survival Organ Preservation Odds ratio Middle Aged Survival Analysis Circulatory death United Kingdom Confidence interval Surgery chemistry Donation business |
| Zdroj: | American Journal of Transplantation. 18:1408-1414 |
| ISSN: | 1600-6135 |
| Popis: | Evidence is currently lacking regarding the outcomes of kidneys undergoing hypothermic machine perfusion (HMP) in patients in the United Kingdom. Using the National Health Service Blood and Transplant database, the authors compared outcomes for recipients of single-organ donation after circulatory death (DCD) kidneys preserved with HMP with those preserved using only static cold storage (SCS). Between 2007 and 2015, HMP was used in 19.1% (864/4,529) of kidneys. Rates of delayed graft function (DGF) were significantly lower in organs preserved with HMP than for organs preserved with SCS (34.2% vs 42.0%, P |
| Databáze: | OpenAIRE |
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