Practical considerations in angiotensin II antibody production
| Autor: | Frantisek Bartos, Richard E. Bailey, Albert Castro, Donald P. Grettie, Dagmar Bartosova, Dorothy Macfarlane |
|---|---|
| Rok vydání: | 1973 |
| Předmět: |
medicine.medical_specialty
Immunogen Macromolecular Substances Polymers Serum albumin chemical and pharmacologic phenomena Cross Reactions complex mixtures Biochemistry Antibody Specificity Internal medicine Renin–angiotensin system medicine Animals Serum Albumin Antiserum biology business.industry Angiotensin II Lysine Radioimmunoassay Titer Endocrinology Immunization Immunology Antibody Formation biology.protein bacteria Rabbits business |
| Zdroj: | Biochemical medicine. 8(1) |
| ISSN: | 0006-2944 |
| Popis: | When cost considerations are paramount, one immunization with angiotensin II-rabbit serum albumin immunogen into multiple sites in rabbits suffices to produce high-titer antisera which are clinically useful for radioimmunoassays. Although sustained antibody responses may occur after one or two immunizations with an angiotensin II-poly- l -lysine immunogen, titers are impractically low for clinical work. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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