Role of phospholipids in iodine binding
| Autor: | James F. Mead, M. Y. Mandlik, R. H. Atmaram, Govind A. Dhopeshwarkar |
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| Rok vydání: | 1968 |
| Předmět: |
Oral dose
medicine.medical_specialty food.ingredient Iron Iodide Phospholipid Thyroid Gland chemistry.chemical_element In Vitro Techniques Iodine Lecithin General Biochemistry Genetics and Molecular Biology chemistry.chemical_compound food Dogs Internal medicine Iodine Isotopes Plasma lipids medicine Methods Animals Magnesium Phospholipids chemistry.chemical_classification Brain Chemistry Chromatography Manganese Binding Sites Thyroid Enzymatic process Rats medicine.anatomical_structure Endocrinology chemistry Liver Injections Intravenous Phosphatidylcholines lipids (amino acids peptides and proteins) Calcium Rabbits Injections Intraperitoneal Protein Binding |
| Zdroj: | Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 129(2) |
| ISSN: | 0037-9727 |
| Popis: | SummaryAfter an oral dose of Na131 I to rats, sacrificed after 48 hr, liver lecithin had maximum radioactivity compared to other phospholipid components; neutral lipids were devoid of any activity. Liver lipids had more activity than thyroid or plasma lipids. Plasma lipids had negligible activity after intravenous injection of Na131I after periods ranging from 15 min to 6 hr. Plasma lecithin does not seem to be a carrier of iodide in the blood. Liver slice or homogenate experiments failed to show any enzymatic process connected with association of lecithin with iodide. |
| Databáze: | OpenAIRE |
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