The Role of Biopsy in the Workup of Patients with Neuroblastoma: Comparison of the Incidence of Surgical Complications and the Diagnostic Reliability of Diverse Techniques
| Autor: | Michele Torre, Irene Paraboschi, Ester Bolognesi, Giuseppe Martucciello, Adele Giannettoni, Stefano Avanzini |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
laparoscopic-assisted core needle biopsy minimally invasive laparoscopic incisional biopsy open incisional biopsy Disease Pediatrics Article RJ1-570 neuroblastoma Neuroblastoma Biopsy Pediatric surgery medicine pediatric surgery Sampling (medicine) medicine.diagnostic_test business.industry Incidence (epidemiology) minimally invasive thoracoscopic incisional biopsy medicine.disease Primary tumor Pediatrics Perinatology and Child Health Radiology business Pediatric population ultrasound-guided core needle biopsy |
| Zdroj: | Children Volume 8 Issue 6 Children, Vol 8, Iss 500, p 500 (2021) |
| ISSN: | 2227-9067 |
| DOI: | 10.3390/children8060500 |
| Popis: | Neuroblastoma (NB) is the most common extracranial solid tumor in childhood, accounting for approximately 15% of all cancer-related deaths in the pediatric population. The overall survival of children with high-risk disease is around 40–50% despite the aggressive treatment protocols. In accordance with the most recent guidelines, a complete classification of the primary tumor, including its histopathological and molecular analysis, is necessary. In this regard, the biopsy of the primary tumor is an important diagnostic procedure adopted not only to confirm the diagnosis but also for staging and risk stratification of the disease. In this study, the authors describe their unicentric experience with four different approaches adopted for sampling NB tumors: (i) the open incisional biopsy (ii) the minimally invasive thoracoscopic/laparoscopic incisional biopsy (iii) the ultrasound-guided core needle biopsy (iv) the laparoscopic-assisted core needle biopsy. The benefits of each technique are analyzed along with their contraindications. |
| Databáze: | OpenAIRE |
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