Clinical correlates of anhedonia in patients with Parkinson's disease
| Autor: | Bungo Okuda, Kiyohiro Matsui, Toshiyuki Yamanishi, Miyako Oguru, Nobuyuki Oka, Hisao Tachibana, Kazuo Toda |
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| Rok vydání: | 2013 |
| Předmět: |
Male
medicine.medical_specialty Parkinson's disease Anhedonia Anxiety Neuropsychological Tests behavioral disciplines and activities Antiparkinson Agents Levodopa Quality of life Rating scale medicine Humans Apathy Psychiatry Depression (differential diagnoses) Aged Psychiatric Status Rating Scales Depression business.industry Beck Depression Inventory Parkinson Disease General Medicine Middle Aged medicine.disease humanities Linear Models Quality of Life behavior and behavior mechanisms Female Surgery Neurology (clinical) medicine.symptom business |
| Zdroj: | Clinical Neurology and Neurosurgery. 115:2524-2527 |
| ISSN: | 0303-8467 |
| Popis: | Objective To investigate the prevalence and clinical correlates of anhedonia in patients with Parkinson's disease (PD) and to also examine the relationship between anhedonia and the QOL. Methods One hundred and seventeen patients with PD completed the Snaith–Hamilton Pleasure Scale (SHAPS), the State–Trait Anxiety Inventory (STAI), the Beck Depression Inventory Second Edition (BDI-II), Starkstein's Apathy Scale (AS) and a quality of life (QOL) battery. Hoehn and Yahr (HY) staging, the Unified Parkinson's Disease Rating Scale (UPDRS) and the Mini-Mental State Examination (MMSE) were administered on the same day. Results Anhedonia (SHAPS score ≥ 3) was diagnosed in 15% of the patients. The SHAPS score was found to be significantly correlated with the HY stage and the UPDRS (I, IVB, IVC, total), BDI-II, AS and STAI (State, Trait) scores. A multivariate analysis revealed that the BDI-II and STAI (Trait) scores significantly influenced the SHAPS scores. The SHAPS scores were found to be negatively correlated with the QOL. Conclusions These findings indicate that anhedonia is associated with depression and anxiety. In addition, recognizing anhedonia in patients with PD is important since it may have a negative effect on the QOL. |
| Databáze: | OpenAIRE |
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