Precise finger somatotopy revealed by focal motor cortex injury
| Autor: | Anthony Mansour, Rechdi Ahdab, Hassan Hosseini, Philippe Kerschen, Samar S. Ayache, Moussa A. Chalah, Jean-Pascal Lefaucheur, Wassim H. Farhat |
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| Přispěvatelé: | Excitabilité nerveuse et thérapeutique (ENT), Hôpital Henri Mondor-EA 4391, Service de Physiologie Explorations Fonctionnelles-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12) |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Weakness [SDV]Life Sciences [q-bio] Movement 050105 experimental psychology Fingers 03 medical and health sciences 0302 clinical medicine Physiology (medical) medicine Humans 0501 psychology and cognitive sciences Muscle Skeletal Stroke Hand muscles Brain Mapping business.industry Ischemic strokes 05 social sciences Motor Cortex General Medicine Adductor digiti minimi Anatomy medicine.disease Evoked Potentials Motor Hand Transcranial Magnetic Stimulation body regions medicine.anatomical_structure Neurology Neurology (clinical) medicine.symptom Functional organization Primary motor cortex business 030217 neurology & neurosurgery Motor cortex |
| Zdroj: | Neurophysiologie Clinique = Clinical Neurophysiology Neurophysiologie Clinique = Clinical Neurophysiology, Elsevier Masson, 2020, 50, pp.27-31. ⟨10.1016/j.neucli.2019.11.001⟩ Neurophysiologie Clinique/Clinical Neurophysiology Neurophysiologie Clinique/Clinical Neurophysiology, Elsevier Masson, 2020, 50, pp.27-31. ⟨10.1016/j.neucli.2019.11.001⟩ |
| ISSN: | 1769-7131 0987-7053 |
| DOI: | 10.1016/j.neucli.2019.11.001⟩ |
| Popis: | Summary Background Somatotopy is considered the hallmark of the primary motor cortex. While this is fundamentally true for the major body parts (head, upper and lower extremities), evidence supporting the existence of within-limb somatotopy is scarce. Method We report a young man presenting recurrent ischemic strokes with selective finger weakness in whom serial motor cortex mapping procedures were performed. Result Following the first stroke, which largely spared the motor cortex, motor mapping displayed overlap of the motor representations of the hand muscles. The second focal stroke, affecting the lateral part of the hand knob, resulted in selective loss of the first dorsal interosseous muscle motor evoked potentials while sparing those of the adductor digiti minimi muscle. This observation is in apparent contradiction with the first mapping results that suggested complete overlap of motor representations. Discussion Our mapping results provide evidence for the existence of very precise within-limb somatotopy and confirm the proposed homuncular order, whereby lateral fingers are represented laterally and medial fingers medially. The discrepancy between the initial and subsequent mapping results is discussed in light of functional organization of the primary motor cortex. |
| Databáze: | OpenAIRE |
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