Interest of a standardized hypnotic message for the reduction of pain and anxiety in cancer patients treated by capsaicin patch for neuropathic pain: a randomized controlled trial
| Autor: | Rémi Etienne, Myriam Laurent, Antoine Bioy, Cécile Huin Schohn, Julia Salleron, Nathalie Cretineau, Aline Henry |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Hypnosis Music therapy medicine.drug_class Administration Topical Pain Anxiety Pain Procedural law.invention Hypnotic Other systems of medicine 03 medical and health sciences 0302 clinical medicine Randomized controlled trial Rating scale law Neoplasms Intervention (counseling) Humans Medicine Aged Cancer 030203 arthritis & rheumatology Analgesics business.industry Research Middle Aged Treatment Outcome Complementary and alternative medicine Neuropathic pain Physical therapy Neuralgia Female Capsaicin medicine.symptom business RZ201-999 030217 neurology & neurosurgery |
| Zdroj: | BMC Complementary Medicine and Therapies BMC Complementary Medicine and Therapies, Vol 21, Iss 1, Pp 1-8 (2021) |
| ISSN: | 2662-7671 |
| DOI: | 10.1186/s12906-021-03329-8 |
| Popis: | Background Neuropathic pain is characterized by spontaneous painful symptoms. Medical therapies include the use of a capsaicin 8% patch (Qutenza®, Grünenthal Gmbh, Germany), and patients may experience a sharp burning sensation at application and removal of the patch. This study aimed to evaluate the impact of playing a standardized hypnosis recording during application, on the pain and anxiety induced by capsaicin treatment. Methods In a randomized, controlled trial, we assessed the benefits of the intervention firstly on pain and secondly on anxiety, as measured using numerical rating scales. All patients had application of the capsaicin patch, including the possibility for the patient to apply a cold patch. Participants were randomly assigned to one of 3 groups, namely the “Standard group” (no intervention), “Hypnosis group”, in which a standardized hypnotic message was played during application, or the “Music group” in which relaxing music was played during application of the patch. Results Sixty-nine patients were included. Overall, there was no significant difference in pain scores between groups (p = 0.355). Compared to standard application, anxiety was significantly lower in the hypnosis group after application (p = 0.007), with no significant difference between the standard and music arms (p = 0.271), or between the hypnosis and music arms (p = 0.423). Conclusions Listening to a standardized hypnotic message during application of a capsaicin patch was found to significantly lower anxiety. These findings indicate that the use of a hypnotic message can reduce discomfort and warrant its evaluation in other indications of pain or anxiety during treatment procedures. Trial registration NCT02822625. |
| Databáze: | OpenAIRE |
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