Warfarin reversal emerging as the major indication for fresh frozen plasma use at a tertiary care hospital

Autor: Barbara O'Malley, Priya Krishen, Bülent Özgönenel, A.B. Eisenbrey
Rok vydání: 2007
Předmět:
Zdroj: American Journal of Hematology. 82:1091-1094
ISSN: 1096-8652
0361-8609
DOI: 10.1002/ajh.20902
Popis: Because of the increase in the use of warfarin in the population in recent years, reversal of warfarin-related coagulopathy has become common in daily hospital practice. Transfusion of fresh frozen plasma (FFP) is the preferred treatment method for urgent warfarin reversal in the USA. We have undertaken a 1-month audit of FFP usage to ascertain the impact of warfarin use on the consumption of FFP. Sixty percent of the 376 units of FFP that were transfused during the study month were used to reverse warfarin effects. The most common reason to reverse warfarin was bleeding. Thirty-three percent of the units were used for the treatment of other coagulopathies, 7% were used in therapeutic plasmapheresis, and
Databáze: OpenAIRE