A facile permethylation of cord factor
| Autor: | Mayer B. Goren, Raoul Toubiana |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
Chromatography
Cord factor Chemical Phenomena Biophysics Molecular sieve Biochemistry Medicinal chemistry Methylation chemistry.chemical_compound Hydrolysis Chemistry Endocrinology chemistry Anhydrous Methods Organic chemistry Dimethylformamide Cord Factors Diethyl ether Glycolipids Dispersion (chemistry) |
| Zdroj: | Biochimica et biophysica acta. 574(1) |
| ISSN: | 0006-3002 |
| Popis: | Small quantities of cord factor (trehalose-6,6'-dimycolates) can be readily and almost quantitatively permethylated in anhydrous diethyl ether/dimethylformamide mixtures with CH3I and NaH-oil dispersion in the presence of molecular sieve. Hydrolysis of the permethylated products from cord factor ‘Peurois’ and ‘P3-Aoyama-B’ prove these to be 6,6'-dimycolates. Experiments with a 4-palmitoyl glucose suggest that acyl migration in this system may not occur. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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