Nanoparticles (NP) as transport systems for the treatment of traumatic brain injury – analysis of the temporal uptake in organs and overcoming the blood-brain barrier of four differently functionalised poly-L-lactide- and poly-perfluorodecyl acrylate–NPs in the rat

Autor: Bechinger, P, Serrano Sponton, L, Eldahaby, D, Jussen, D, Krenzlin, H, Grützner, V, Riede, N, Musyanovich, A, Ottenhausen, M, Ringel, F, Alessandri, B
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: 73. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Griechischen Gesellschaft für Neurochirurgie; 20220529-20220601; Köln; DOCP195 /20220525/
DOI: 10.3205/22dgnc509
Popis: Objective: A growing interest exists in using polymeric nanoparticles (NPs) especially functionalized with surface-active substances as carriers across the blood-brain barrier (BBB) for potentially effective drugs in traumatic brain injury (TBI). However, a matter requiring further research remains [for full text, please go to the a.m. URL]
Databáze: OpenAIRE