Improving psychotropic drug prescription in nursing home patients with dementia

Autor: Martin Smalbrugge, Debby L. Gerritsen, Claudia H. W. Smeets, Klaas van der Spek, Marjorie H. J. M. G. Nelissen-Vrancken, Raymond T. C. M. Koopmans, Roland B Wetzels, Sytse U Zuidema
Přispěvatelé: Life Course Epidemiology (LCE), General practice, EMGO - Quality of care
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Research design
medicine.medical_specialty
Activities of daily living
Psychotropic drugs
OF-LIFE INSTRUMENT
SOCIAL ENGAGEMENT
DUTCH VERSION
Nursing homes
Drug Prescriptions
ELDERLY-PEOPLE
law.invention
Medication safety
Study Protocol
Clinical Protocols
Randomized controlled trial
NEUROPSYCHIATRIC INVENTORY
Alzheimer Disease
law
MEDICATION USE
Activities of Daily Living
Humans
Medicine
Dementia
Medical prescription
Psychiatry
OLDER-ADULTS
GeneralLiterature_REFERENCE(e.g.
dictionaries
encyclopedias
glossaries)
Aged
Netherlands
ALZHEIMER-DISEASE
Aged
80 and over
business.industry
MANSFIELD AGITATION INVENTORY
Effective primary care and public health [NCEBP 7]
medicine.disease
Clinical trial
Long-term care
Psychiatry and Mental health
Psychotropic drug
Research Design
Quality of Life
LONG-TERM-CARE
business
Zdroj: Smeets, C H, Smalbrugge, M, Gerritsen, D L, Nelissen-Vrancken, M H, Wetzels, R B, van der Spek, K, Zuidema, S U & Koopmans, R T 2013, ' Improving psychotropic drug prescription in nursing home patients with dementia: design of a cluster randomized controlled trial ', BMC Psychiatry, vol. 13, 280 . https://doi.org/10.1186/1471-244X-13-280
BMC Psychiatry, 13:280. BMC
BMC Psychiatry, Nov 1;13, 1, pp. 280
BMC Psychiatry
BMC Psychiatry, 13:280. BioMed Central
BMC Psychiatry, Nov 1;13, 280
ISSN: 1471-244X
Popis: Background Neuropsychiatric symptoms are highly prevalent in nursing home patients with dementia. Despite modest effectiveness and considerable side effects, psychotropic drugs are frequently prescribed for these neuropsychiatric symptoms. This raises questions whether psychotropic drugs are appropriately prescribed. The aim of the PROPER (PRescription Optimization of Psychotropic drugs in Elderly nuRsing home patients with dementia) II study is to investigate the efficacy of an intervention for improving the appropriateness of psychotropic drug prescription in nursing home patients with dementia. Methods/design The PROPER II study is a multi-center cluster randomized controlled, pragmatic trial using parallel groups. It has a duration of eighteen months and four six-monthly assessments. Six nursing homes will participate in the intervention and six will continue care as usual. The nursing homes will be located throughout the Netherlands, each participating with two dementia special care units with an average of fifteen patients per unit, resulting in 360 patients. The intervention consists of a structured and repeated multidisciplinary medication review supported by education and continuous evaluation. It is conducted by pharmacists, physicians, and nurses and consists of three components: 1) preparation and education, 2) conduct, and 3) evaluation/guidance. The primary outcome is the proportion of patients with appropriate psychotropic drug use. Secondary outcomes are the overall frequency of psychotropic drug use, neuropsychiatric symptoms, quality of life, activities of daily living, psychotropic drug side effects and adverse events (including cognition, comorbidity, and mortality). Besides, a process analysis on the intervention will be carried out. Discussion This study is expected to improve the appropriateness of psychotropic drug prescription for neuropsychiatric symptoms in nursing home patients with dementia by introducing a structured and repeated multidisciplinary medication review supported by education and continuous evaluation. Trial registration Netherlands Trial Registry (NTR): NTR3569.
Databáze: OpenAIRE
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