Paracorporeal assistance system for restoring cardiac activity
| Autor: | L. F. Koblov, A. E. Kuvaev, Gasanov Ek, Tolpekin Ve |
|---|---|
| Rok vydání: | 1987 |
| Předmět: |
medicine.medical_specialty
Biomedical Engineering Pump function Medicine (miscellaneous) Hemodynamics Bioengineering Cardiac activity Biomaterials Internal medicine medicine Animals Assisted Circulation Heart-Assist Devices Fibrillation business.industry Adenine Nucleotides Myocardium General Medicine medicine.disease Myocardial Contraction Electrophysiology medicine.anatomical_structure Ventricle Evaluation Studies as Topic Anesthesia Ventricular fibrillation Ventricular Fibrillation Cardiology Cattle medicine.symptom business Energy Metabolism Perfusion |
| Zdroj: | Artificial organs. 11(1) |
| ISSN: | 0160-564X |
| Popis: | Two series of experiments were conducted to assess the potential of artificial ventricular bypass in restoring cardiac activity. One series evaluated use of a paracorporeal left ventricle in 17 calves; the other evaluated biventricular bypass in 11 calves. Module pumps with a seamless blood chamber of polyurethane were used. Pump function and system parameters were controlled by a Sinus VK-2 control system. Assisted perfusion began with the induction of ventricular fibrillation. The experiments showed that left ventricular bypass was an effective method for long-term maintenance of the hemodynamics during fibrillation, leading to certain biochemical corrections and restored electrical activity and myocardial contractile function. The hemodynamic state was maintained at a higher level with biventricular bypass and was accompanied by a greater percentage of restored myocardial function. Uneven restoration of contractile activity in the left and right ventricles points to the need for adequate support of both ventricles. |
| Databáze: | OpenAIRE |
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