A comparison between radiation therapists and medical specialists in the use of kilovoltage cone-beam computed tomography scans for potential lung cancer radiotherapy target verification and adaptation
| Autor: | Lois Holloway, Marion Dimigen, John Atyeo, Branimere Zogovic, Sian Wallis, Joseph Descallar, Shalini K Vinod, Sandie Carolyn Watt |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Kilovoltage Cone Beam Computed Tomography
medicine.medical_specialty Lung Neoplasms medicine.medical_treatment Adaptation (eye) 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Medicine Humans Radiology Nuclear Medicine and imaging Lung cancer Image-guided radiation therapy Radiological and Ultrasound Technology Radiation Therapist business.industry Isocenter Cone-Beam Computed Tomography medicine.disease Radiation therapy Oncology 030220 oncology & carcinogenesis Tomography Radiology Clinical Competence business Nuclear medicine Radiotherapy Image-Guided |
| Zdroj: | Medical dosimetry : official journal of the American Association of Medical Dosimetrists. 41(1) |
| ISSN: | 1873-4022 |
| Popis: | Target volume matching using cone-beam computed tomography (CBCT) is the preferred treatment verification method for lung cancer in many centers. However, radiation therapists (RTs) are trained in bony matching and not soft tissue matching. The purpose of this study was to determine whether RTs were equivalent to radiation oncologists (ROs) and radiologists (RDs) in alignment of the treatment CBCT with the gross tumor volume (GTV) defined at planning and in delineating the GTV on the treatment CBCT, as may be necessary for adaptive radiotherapy. In this study, 10 RTs, 1 RO, and 1 RD performed a manual tumor alignment and correction of the planning GTV to a treatment CBCT to generate an isocenter correction distance for 15 patient data sets. Participants also contoured the GTV on the same data sets. The isocenter correction distance and the contoured GTVs from the RTs were compared with the RD and RO. The mean difference in isocenter correction distances was 0.40cm between the RO and RD, 0.51cm between the RTs, and RO and 0.42cm between the RTs and RD. The 95% CIs were smaller than the equivalence limit of 0.5cm, indicating that the RTs were equivalent to the RO and RD. For GTV delineation comparisons, the RTs were not found to be equivalent to the RD or RO. The alignment of the planning defined GTV and treatment CBCT using soft tissue matching by the RTs has been shown to be equivalent to those by the RO and RD. However, tumor delineation by the RTs on the treatment CBCT was not equivalent to that of the RO and RD. Thus, it may be appropriate for RTs to undertake soft tissue alignment based on CBCT; however, further investigation may be necessary before RTs undertake delineation for adaptive radiotherapy purposes. |
| Databáze: | OpenAIRE |
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